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    I've been blogging occasionally over the last two months about my ongoing experiment with writing articles. This is a super hot topic lately with the changes going on at Google and Yahoo that are impacting many websites and basically freaking people
    According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product
    out.

    Now everybody knows that writing articles is a powerful technique. You knew that, right? And everybody is writing articles, right? No. Did I? Not until recently, though I wrote a lot in blogs and did post some articles I wrote on my sites.
    ; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

    Examples of combination products may in
    There's two parts to this for me. Writing, which I have been doing. Distributing. Which I hadn't been doing.

    I finally came out of that fog and decided that I had to see what distribution might really do. Content, such as original articles is s
    lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

    ill the basic currency of the internet. People come onto the web looking for information. Content provides that information.

    But, if the content is just sitting on a blog or posted in an article directory on one website, it has very limited expos
    here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe
    ure without links. Content may be the flesh of the web, but links are the bones, the underlying structure that allows things to found and accessed.

    It's in our faces right here - the two basics that you can combine to really power a successful web
    d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

    Combination pro
    ite. Content and links. Write articles AND publish/distribute them. Simple, basic, old style site building.

    One technique many are using to build sites is to get other people's articles and put them up on their sites to provide related content.
    ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc
    I do it, you do it, nearly everyone seems to. Other people publish ezines, but can't possibly write all the content they want to provide. This is the demand that exists, right now, for your articles. There is a deep, apparently bottomless need fo
    easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi
    quality content on nearly anything imaginable. And it won't go away.

    Original content on your site is a great traffic booster. Distributing your content all over the internet gets you lots of incoming links - which over time could well continue to
    nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically
    increase as your articles are picked up and redistributed. Plus you are generating a name for yourself and qualifying yourself as an expert. Experts write about what they know and discover. They share their knowledge. I'm not talking about anyo
    and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ
    e being a genius and discovering anti-gravity (and finally eliminating rocket science). I'm talking about what's already in your head and what you can learn, research and write about.

    I wrote three articles on some basics concepts to keep in mind
    ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi
    in building and developing successful eCommerce websites. They aren't hot hot hot 6 steps to infinite wealth type writing. They're basic and based on research. Then I distributed them to a couple (not all) of the big article directories and to a
    ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

    Following aspects would a
    large group of relevant directories and lists through SubmitYourArticle.com (which I do recommend if you're looking for an excellent and reasonable article submission service). Here are the results as of this writing (June 28, 2005):

    ======== Page
    dd to the challenges in developing combination products:

    Which markets to tap where the combination products can do fairly well?
    Which combination prod
    Reported
    ======== Yahoo = Google = MSN = Pub Date
    Article 1 . . . 610 . . . 320 . . . . 436 . . May 19th
    Article 2 . . . 253 . . . 246 . . . . 269 . . June 1st
    Article 3 . . 2060 . . .1000 . . . .239 . . June 14th

    . . Total
    cts are meaningful and rational?
    Which therapeutic categories to select?
    Which Combinations can address unmet needs of the patients?
    Do combin
    . . .2923 . . .1566 . . . .944

    That's a lot of pages. Now, some of those won't have any live link. Yes, it does happen even though it really shouldn't. A lot of the sites it's on won't have much or any page rank and probably quite a few sites are
    tions increase the patient compliance?
    What would be the developing cost?
    How to tackle the risks encountered during combination product developmen
    ot relevant. People aren't always careful about selecting relevant articles. Some will be on pages that won't pass rank. However, what's left are relevant incoming one-way links - some of which will be from sites with at least some authority. Say
    t?

    As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel
    even 20% of the links are relevant and/or from sites with some rank. That's a minimum (I believe I'm being pretty conservative with the 20% figure) of over 1000 useful incoming links based on relevant content.

    I was astonished. And then I felt re
    ping new procedures for reviewing their safety, efficacy and quality.

    Professional from academic institutions, pharmaceutical industries, health care indust
    lly stupid - I knew this, but I really didn't GET it or I would have been writing and distributing from day 1. You're looking at the truth behind the power of articles and article distribution. No tricks, no fancy high powered tools, no big expensi
    y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products
    ve anything at all.

    Are you telling yourself you can't write articles? I'm telling you that you can. If you can talk, you can write. If you need help, there are lots of resources about how to write - some very good ones are free, some are quite in
    .

    As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de
    xpensive. Other tools are more expensive.

    Ghostwriters are another alternative. A little tricky and possibly slightly expensive for really high quality work, but there's also a lot of information available on how to do it right.

    My advice here is
    elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

    Companies that provide selfless information through particip
    - whatever it takes, start publishing your own original content on your website and start distributing it now. For building long term success, there's very little you can do that will have anywhere near the same results.

    Copyright 2005 Richard Kei


    tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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