Top Reference - Computers and Technology

1. You turn the PC on, it loads through and then reports it cannot find the C Drive

This sounds like a fault hard disk, swap it with another from a working PC, if the problem reso

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

lves this way then your drive is bad. The hard drive is found inside the case, it will have a ribbon attached to the mainboard and one of the power leads from the PSU. It is fixed

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

with screws into the case, undo these, whip out the cables and get yourself a new disk.

Sometimes a reboot will give your disk a little more life, if a reboot does help, then mak

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

e sure you backup your data straight away and get a new disk in there! This is a best case scenario, normally if the C Drive dies you lose all your data, if you can save it this wa

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

y then you were lucky!

2. No activity when turning the computer on

You hear nothing, no lights start frantically flashing at you, nothing appears on the screen? First things firs

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

, check that it is plugged in!!!

Okay enough of the sillyness, the thing is plugged in, it now seems like the PSU (Power Supply Unit) has died a horrible death! The PSU is a box n

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

ormally at the back of your computer held into the case by 4 screws and has a fan blowing bad air out of the back! There is also a wiring loom that comes from this dreaded box into

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

the main board of the pc. It is this wire that feeds electricity to all of the components inside your PC! Unplug all these power wires and unscrew the PSU, you can now take it to

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

the PC Store and show the guys there, they will then get you a new one!

3. Regular Blue Screen Errors, sounds like a memory problem to me!

You are using your PC, happily writing

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

documents or surfing the Internet, when BAM, Blue Screen of Death is telling you there was a fatal error and your computer needs to be put into the retirement home. Fear not, 9 out

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

of 10 times this is just unfortunate and unavoidable, but a restart will cure it. However, if you keep getting this regularly then you may have a RAM (Random Access Memory) problem

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

. This is again easily fixable using other memory sticks. If you have a PC that works fine, try swapping the memory sticks to see if this remedies your problem. You can get memory

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

testers that can tell you if your RAM is bad, try running one of these. If you do end up with a bad RAM stick, then nip down to the store and buy a new one!

RAM sticks fit into th

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

e main board normally not far from the processor. Just flip the little switches at either and and pull the old one out, line up the new one with the slots and push down. Once you h

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

ear a click at both ends, you're ready to go!

4. The computer starts up, but the monitor is blacker than the black hole of calcutta!

Basically this means your monitor has had it.

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

Again check it is plugged in etc. If you have a different monitor lying around you can use, try plugging that in. If it works then it's a safe bet the first one is ready for the sc

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

rap heap. Monitors store electricity inside them using capacitors, don't every try to repair one!!! This stored electricity has the potential to kill you!!!

If the monitor does co

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

me on (Power Light is shining bright) but the screen is black, then it could be a Video Card problem. Firstly identify the Video Card in your PC, should be pretty easy, it has the

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

monitor plugged into it. If it is part of the main board then you can't do much about it buster, however if it is seperate be sure it is firmly pushed into it's little slot, if thi

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

s does no good, then remove the card and get yourself a new one. They are fairly inexpensive unless you are a serious gamer, then you could be looking at the hundreds and thousands

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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