Top Reference - Food and Drink

You've seen FTGFOP, BOP, CTC on labels of tea...

What do these codes mean?

These codes are used to

According to USFDA, a combination product is one composed of any combination of a drug and device; biological product and device; drug and biological product

classify single estate teas such as Darjeeling, Ceylon, and Assam. At the end of a tealeaf makeing process,

; or drug, device, and biological product and fixed dose combination would include two or more combinations of drug.

Examples of combination products may in

machine will separate the tealeaves according to their type, size, and categorize them into different grades

lude drug-coated devices, drugs packaged with delivery devices in medical kits, and drugs and devices packaged separately but intended to be used together.

.

Letters like P: Pekoe, O: Orange, B: Broken, etc, are connected to indicate the different grades

here is enormous increase in the number of combination products entering the market in the recent years. Combination products have proven advantages but fixe

of the black tea.

Here is a summary of the most commonly used codes:

OP: Orange Pekoe

d dose combinations are still in the process of convincing regulatory authority on their advantages over the single ingredient formulations.

Combination pro

Usually refers to relatively longer and complete tealeaf.

BOP: Broken Orange Pekoe
Refers to b

ucts have become life saving products for the pharmaceutical companies who doesn’t have many innovative molecules in their product pipeline and have been inc

roken orange pekoe. They make a stronger brew than OP, so they are more suitable to make milk tea.

easingly used in the product life cycle management. Even the companies having product patents are trying to extend their product life cycle through the combi

b>FOP: Flowery Orange Pekoe
Refers to tealeaves that have buds, which would create a floral fragranc

nation products and maximize the revenues. But the companies involved in this practice are overlooking that they are burdening the patients both economically

in the tea.

FBOP: Flower Broken Orange Pekoe
Contains both buds and broken tea leaves.

and physically. They need to rightly judge the benefits of the combination products and they have to even look at the risks involved when combining the produ

Makes a stronger tea with floral fragrance.

TGFOP: Tippy Golden Flowery Orange Pekoe
Co

ts. Some of the combination products were well accepted by physicians while others suffered. Companies involved in development of combination products are fi

tains young buds, which appear golden. Makes a much more fragrant and strong tea than FOP.

FTGFO

ding difficulty in defining their combination products and facing various challenges from selecting a combination to marketing it.

Following aspects would a

: Fine(est) Tippy Golden Flowery Orange Pekoe
Very high quality tea that went through an extra proce

dd to the challenges in developing combination products:

Which markets to tap where the combination products can do fairly well?
Which combination prod

dure of rolling, which would draw out the best flavour in tea.

SFTGFOP: S stands for Super or

cts are meaningful and rational?
Which therapeutic categories to select?
Which Combinations can address unmet needs of the patients?
Do combin

Special. The meaning is obvious.

CTC: Crush, Tear, Curl
These teas are compressed int

tions increase the patient compliance?
What would be the developing cost?
How to tackle the risks encountered during combination product developmen

small pieces by a special machine. CTC leaves make a very strong brew in short amount of time. It is ideal

t?

As combination products don't fit into the traditional categories of drugs, medical devices, or biological products, the USFDA is in the process of devel

for consuming with milk.

Others: Fanning, Dust
Refers to very small pieces of te

ping new procedures for reviewing their safety, efficacy and quality.

Professional from academic institutions, pharmaceutical industries, health care indust

leaves. Usually used in India to make Chai or milk tea.

Sometimes, there is a "1" at the end

y and representatives from various regulatory agencies are working out to design the regulatory requirements for manufacture and sale of combination products

of a tea name, such as FOP1 or FTGFOP1. It means the first grade of that particular tea: FOP1 means the firs

.

As there is an increasing trend of the combination products companies manufacturing such products should be able to tackle the problems involved in the de

t grade of that FOP.

The number of letters, however, does not necessarily mean the quality of tea. Some

elopment. They need to be wiser in analyzing the market trends and the regulatory requirements.

Companies that provide selfless information through particip

people prefer BOP instead of FTGFOP becuase BOP makes stronger tea, which is suitable for consuming with milk

tion in industry events and feedback to regulatory authorities would be able to face the challenges and will be successful in developing combination products

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